Each tablet is\u00a0packaged separately in the blister pack and enteric coated for\u00a0protection from moisture\/light to ensure a biologically active product\u00a0(SAMe is unstable and needs extra protection).<\/p>\n
60 Tablets, 400mg SAMe (S-Adenosyl-Methionine) in each tablet.\u00a0<\/p>\n
SAMe is a naturally occurring molecule found in all living cells, but many are depleted. SAMe gives away a methyl group when converted to SAH in your cells, and is the key nutrient in the methylation cycle.<\/em><\/p>\n <\/strong><\/span>SAMe is largely known for its effects on optimal mood and has also shown benefits for the liver, brain, and joints.<\/span><\/p>\n SAMe may become depleted with sickness, age or slow methylation. Supplementing with SAMe plus folate, trimethylglycine (TMG or betaine), vitamins B6 and B12 appears to be an effective way to overcome this deficiency. You will find all the cofactors in VITAcure Methyl Plus.<\/span><\/p>\n SAMe is concentrated in the liver and brain and is a major methyl donor in the synthesis of hormones, nucleic acids, proteins, and phospholipids, and catecholamines and other neurotransmitters. SAMe is required for the synthesis of norepinephrine, dopamine, and serotonin.<\/span> <\/span>SAMe facilitates glutathione<\/span>\u00a0usage, which improves the antioxidant defense. It also helps maintain acetylcholine levels<\/span>\u00a0which are necessary for cognitive function.<\/span><\/p>\n SAMe is used by the body in three important pathways<\/strong>:\u00a0<\/span>Methylation<\/strong> (contributing methyl groups to activate certain molecules), The synthesis of polyamines<\/strong> (for cell growth, gene expression, neuronal regeneration, etc.) & Trans-sulfuration<\/strong> (synthesis of cysteine, glutathione, and other sulfate chemicals).<\/p>\n Caution: SAMe should not be taken by those diagnosed with bipolar disorder, especially over-methylated (the undermethylated bipolar\u00a0might take SAMe when depressed, but watch out for signs of mania and then stop if mania is approaching).\u00a0<\/span><\/p>\n Supplement Facts: <\/strong><\/span><\/p>\n Serving Size: <\/strong>1 enteric coated tablet.<\/span><\/p>\n Amount Per Serving:<\/strong> S-Adenosyl-Methionine…400 mg. <\/span><\/p>\n Other Ingredients: cellulose, mannitol, hydroxypropyl methylcellulose phthalate, citric acid, stearic acid, silica, glyceryl triacetate, sodium starch glycolate, croscarmellose sodium, titanium dioxide, yellow ochre.\u00a0<\/em><\/p>\n Dosage and Use: Take one (1) tablet one to three times daily in divided doses, preferably on an empty stomach, or as recommended by a healthcare practitioner. Take with co-factors.<\/span>\u00a0<\/p>\n Warnings:\u00a0<\/b><\/span>KEEP OUT OF REACH OF CHILDREN. \u00a0DO NOT EXCEED RECOMMENDED DOSE.\u00a0<\/p>\n When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.<\/p>\n \u00a0<\/p>\n